Histamine’s broad role in our bodies makes it relevant to nearly every major system. As such, dysregulated histamine can impact nearly every major system. Be it from a downregulated HNMT gene, excess histamine consumption, or gut dysbiosis — resulting sometimes in histamine intolerance (HIT) — can wreak absolute havoc on a body.
Both dietary and genetic considerations dictate the dynamics of histamine in our bodies. Research shows those with certain genetic variations are more susceptible to histamine dysregulation. Further complexity arises from the influence of certain foods and supplements on histamine.
Antihistamines are among the most valued over-the-counter (OTC) medications to the United States healthcare system. These non-prescription medications address health conditions characterized by respiratory issues, skin issues, and many more (9).
These OTC medications work by targeting histamine receptors throughout the body. By binding to these sites, antihistamines can effectively reduce the influence of histamine molecules which are known to produce symptoms of allergic response such as indigestion, dry or itchy eyes, runny nose, and itchy skin.
Histamine plays a pivotal role in the response to allergens in the human body. …
These effects were noted by observing changes in immune cell activity, expression of immunological genes, and blood pressure measurements. These findings highlight a growing concern over the negative impact of air pollution on health and help to describe with more exact detail the true nature of air pollution’s impact on the developing immune system.
The study, led by Stanford-based researcher Mary Prunikci (1), describes the negative impact of exposure to common air pollutants such as wildfire smoke, car exhaust, and ground-level ozone.
The research team monitored immunological changes in school-aged children over the course of a year to estimate how…
Before we take a look at getting the weekday name, let’s consider how Python’s
datetime class gets a date and subsequently determines the day of the week for said date. There’s nothing fancy about it, but it pays to know where you’re starting.
This code illustrates how far the
datetime class will get you before you have to start getting creative. Before we move on, there are two things worth noting:
weekdaymethod assigns the value
isoweekday, assigns the value
Check out the official
datetime.weekday documentation for more info. Now…
Each year, GitHub publishes The State of the Octoverse (SOTO) — a comprehensive analysis of user data. This annual report looks at things like geographics, gender, usage data, and tons more. When it comes to gathering usage data for programming languages — what better source than GitHub?
Amidst the SOTO report is a listing of the most popular programming languages — determined by total repository accumulation — measured over the past 6 years (2014-). While there are hundreds of languages out there, these are the top 10 most popular programming languages:
Python is one of the world’s most popular programming languages for good reason — it provides powerful built-in data types to handle common problems. The
set datatype can be used for performant collections where uniqueness is required. Python
sets are more performant than
listswhen it comes to lookups but slightly less performant when iterating over elements.
Python sets provide several methods by which elements can be added, removed, or retrieved. The most straightforward(ish) method is the
set.add() method. The official Python documentation describes sets in the following way (R):
“A set is an unordered collection with no duplicate elements. Basic…
Other libraries, most notably the Python Requests library, can provide a clearer API for those more concerned with higher-level operations. This article outlines three ways to download a file using Python with a short discussion of each.
Python’s urllib library offers a range of functions designed to handle common URL-related tasks. This includes parsing, requesting, and — you guessed it — downloading files. Let’s consider a basic example of downloading the
robots.txt file from www.google.com:
urlretrieve is considered “legacy” from Python 2 and, in the words of the Python documentation, “might become deprecated at some point in…
Modern translation pipelines often make use of distributed systems like cloud-based solutions, dynamic link libraries, and virtualization. Advances in translation strategies are nothing short of inspiring. At their heart, however, these pipelines encompass several fundamental steps having been taken by Computer Scientists for decades.
Reliable data transfer protocols (RDT, RDP) are algorithmic measures to provide assurances of the reliable transfer of data across a network that may be subject to data loss and/or corruption. RDT involves sender-side and receiver-side sequences and variables to validate, acknowledge, and retransmit data when necessary.
The goal of RDT protocols is to provide network and link layer service such that application and transport layer services can make guarantees about data delivery.
Reliable Data Transfer Protocols must address the two primary concerns of data loss and data corruption. …
These services allow ensuring a certain level of operability such that higher-layered protocols can take the lower-level features for granted. Another benefit is that developers of layer-specific applications can focus on their primary goals rather than wrestling with the functionality of other layers.
For example, in TCP/IP communication, the transport layer offers a Reliable Data Protocol (RDP) service. This allows developers to focus on the logic of networked applications rather than the delivery of generated data.
For example, web browsers can use HTTP protocol — an application layer protocol — to ensure communication between clients and hosts are facilitated without…
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